Product Name: MK-5108
Synonyms: trans-4-(3-chloro-2-fluorophenoxy)-1-[[6-(2-thiazolylamino)-2-pyridinyl]methyl]-cyclohexanecarboxylic acid VX-689Web Site click
Product Overview: A potent inhibitor of Aurora A (IC50 = 0.064 nM) that less potently inhibits Aurora B and Aurora C (IC50s =14 and 12 nM, respectively); blocks cell cycle progression and induces apoptosis in a diverse range of human tumor types; effective in vivoThe Auror
Shipping: wet ice
CAS NO: 821794-92-7 Product: FMK
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C22H21ClFN3O3S
SMILES: ClC1=C(F)C(O[C@@H]2CC[C@@](CC3=CC=CC(NC4=NC=CS4)=N3)(C(O)=O)CC2)=CC=C1DNA-PK inhibitors
Molecular Weight: 461.9
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/60/8/5006.abstract
