Product Name: MK-2461
Synonyms: Web Site click
Product Overview: MK-2461 is a potent, multi-targeted inhibitor for c-Met(WT/mutants) with IC50 of 0.4-2.5 nM, less potent to Ron, Flt1; 8- to 30-fold greater selectivity of c-Met targets versus FGFR1, FGFR2, FGFR3, PDGFRβ, KDR, Flt3, Flt4, TrkA, and TrkB. Phase 1/2.
Shipping: wet ice
CAS NO: 152811-62-6 Product: Piboserod
Stability: Store at +4 degrees; shelf life 730 days maximum after production
Molecular Formula: C24H25N5O5S
SMILES: Checkpoint Kinase (Chk) inhibitors
Molecular Weight: 495.55
Formulation: A crystalline solid
Purity: 0.98PubMed ID:http://aac.asm.org/content/46/12/3997.abstract
