Product Name: MK-0812
Synonyms: 1,5-anhydro-2,3-dideoxy-3-[[(1R,3S)- 3-[[7,8-dihydro-3-(trifluoromethyl)-1,6-naphthyridin-6(5H)-yl]carbonyl]-3-(1-methylethyl)cyclopentyl]amino]-4-O-methyl-D-erythro-pentitolMedchemexpress
Product Overview: A potent CCR2 antagonist (IC50 = 5 nM for human CCR2); not efficacious in a mouse model of arthritis or in clinical trials for rheumatoid arthritis and multiple sclerosisMK-0812 is a potent C-C chemokine receptor type 2 (CCR2) antagonist (IC50 = 5 nM for
Shipping: dry ice
CAS NO: 80433-71-2 Product: Levoleucovorin (Calcium)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C24H34F3N3O3
SMILES: O=C([C@@]1(C(C)C)CC[C@@H](N[C@]2([H])[C@H](OC)COCC2)C1)N(C3)CCC4=C3C=C(C(F)(F)F)C=N4NF-(kappa)B inhibitors
Molecular Weight: 469.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/49/4/1279.abstract
