Product Name: Luotonin A
Synonyms: quino[2,3:3,4]pyrrolo[2,1-b]quinazolin-11(13H)-oneMedchemexpress.com
Product Overview: An alkaloid that inhibits the growth of mouse leukemia P388 cells (IC50 = 1.8 μg/ml); binds to and stabilizes the topoisomerase I-DNA binary complex, leading to DNA breakage and cell death (IC50 = 5.07-12.6 μM); selectively inhibits CYP1A1 and CYP1A
Shipping: wet ice
CAS NO: 107-43-7 Product: Betaine
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C18H11N3O
SMILES: O=C1N2C(C(N=C(C=CC=C3)C3=C4)=C4C2)=NC5=CC=CC=C51NEDD8-activating Enzyme inhibitors
Molecular Weight: 285.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/58/6/3389.abstract
