Product Name: β-Lapachone
Synonyms: 3,4-dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione ARQ 501 Web Site click
Product Overview: A quinone which inhibits topoisomerase I at 25 μM and transglutaminase (IC50 = 5 μM); reduced to β-lapachone hydroquinone by NQO1, generating ROS during its reversion to β-lapachone; sensitizes cancer cells to radiation, suppresses NF-&kap
Shipping: wet ice
CAS NO: 1133432-49-1 GDC-0834
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C15H14O3
SMILES: O=C(C1=C(C2=C3CCC(C)(C)O2)C=CC=C1)C3=OAPC inhibitors
Molecular Weight: 242.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/4/402
