Product Name: LY364947
Synonyms: 4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]-quinoline HTS 466284 Medchemexpress.com
Product Overview: A selective inhibitor of TGF-β RI, with an IC50 value of 59 nM; poorly inhibits TGF-β RII (IC50 = 400 nM), p38 MAPK (IC50 = 740 nM), and MLK7 (IC50 = 1,400 nM); inhibits TGF-β-induced cell growth (IC50 = 89 nM) and Smad phosphorylationTrans
Shipping: wet ice
CAS NO: 1426802-50-7 ROR gamma-t-IN-1
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C17H12N4
SMILES: C1(C2=CC=NC3=C2C=CC=C3)=CNN=C1C4=NC=CC=C4Tyrosinase inhibitors
Molecular Weight: 272.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/54/5/2188.abstract
