Product Name: LY2874455
Synonyms: 4-[(1E)-2-[5-[(1R)-1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanolMedchemexpress
Product Overview: A pan-FGFR inhibitor (IC50s = 2.8, 2.6, 6.4, 6, and 7 nM for FGFR1, FGFR2, FGFR3, FGFR4, and VEGFR2, respectively); inhibits proliferation of KMS-11, OPM-2, SNU-16, and KATO-III cancer cells in vitro and in tumor xenografts in mice,LY2874455 is a pan-inhi
Shipping: dry ice
CAS NO: 379270-37-8 Product: GS-7340
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H19Cl2N5O2
SMILES: ClC1=C([C@@H](C)OC2=CC(C(/C=C/C3=CN(CCO)N=C3)=NN4)=C4C=C2)C(Cl)=CN=C1PDGFR inhibitors
Molecular Weight: 444.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/48/3/1032.abstract
