Product Name: LE 135
Synonyms: 4-(7,8,9,10-tetrahydro-5,7,7,10,10-pentamethyl-5H-benzo[e]naphtho[2,3-b][1,4]diazepin-13-yl)-benzoic acidMedchemexpress
Product Overview: A RAR antagonist with moderate selectivity for RARβ over RARα (Kis = 0.22 and 1.4 μM, respectively); inhibits retinoid Am80-induced differentiatiobn of HL-60 cells (IC50 = 0.2 μM)LE 135 is a retinoic acid receptor (RAR) antagonist that di
Shipping: wet ice
CAS NO: 852475-26-4 Product: MC1568
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C29H30N2O2
SMILES: CC1(C)C2=C(C=C(N(C)C(C=CC=C3)=C3C(C4=CC=C(C(O)=O)C=C4)=N5)C5=C2)C(C)(C)CC1Farnesyl Transferase inhibitors
Molecular Weight: 438.6
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/57/2/930.abstract
