Product Name: Ku-0060648
Synonyms: 4-ethyl-N-[4-[2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-8-yl]-1-dibenzothienyl]-1-piperazineacetamideMedchemexpress.com
Product Overview: A dual inhibitor of DNA-PK and PI3KKu-0060648 is an ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK) and an inhibitor of PI3K. In a cell-free assay, it has IC50s of 5, 4, 0.5, 50s of 19 and 39 nM, for DNA-PK and PI3K, respectively, while
Shipping: wet ice
CAS NO: 58020-43-2 Product: HOKU-81
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C33H34N4O4S
SMILES: O=C(CN1CCN(CC)CC1)NC2=CC=C(C3=CC=CC4=C3OC(N5CCOCC5)=CC4=O)C6=C2C(C=CC=C7)=C7S6Mineralocorticoid Receptor inhibitors
Molecular Weight: 582.7
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/60/5/2671.abstract
