Product Name: K-Ras(G12C) Inhibitor 12
Synonyms: 1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)amino]acetyl]-1-piperazinyl]-2-propen-1-oneWeb Site：Medchemexpress
Product Overview: An allosteric inhibitor of oncogenic K-Ras(G12C); decreases viability and increases apoptosis in several lung cancer cell lines that contain G12C mutations (EC50 = 0.32 µM in H1792 cells)K-Ras(G12C) inhibitor 12 irreversibly binds to the oncogenic m
Shipping: wet ice
CAS NO: 467458-02-2 Product: Lu AE58054 (Hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C15H17ClIN3O3
SMILES: IC1=C(Cl)C=C(O)C(NCC(N2CCN(C(C=C)=O)CC2)=O)=C1Pim inhibitors
Molecular Weight: 449.7
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/59/12/7842.abstract
