Product Name: HTH-01-015
Synonyms: 5,13-dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-oneMedchemexpress.com
Product Overview: A selective inhibitor of NUAK1 (IC50 = 100 nM); partially inhibits the phosphorylation of the NUAK1 substrate MYPT1 at Ser445; inhibits proliferation and migration of mouse embryonic fibroblasts and U2OS cells at 10 µM in cell-based assaysNUAK1 (als
Shipping: wet ice
CAS NO: 1062368-62-0 Product: LDN193189 (Hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C26H28N8O
SMILES: CC1=C(N(C)C(C2=CC(C=CC=C3)=C3C=C2N4C)=O)C4=NC(NC5=CN(N=C5)C6CCNCC6)=N1RIP kinase inhibitors
Molecular Weight: 468.6
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/60/8/4442.abstract
