Product Name: HS-173
Synonyms: 6-[5-[(phenylsulfonyl)amino]-3-pyridinyl]-imidazo[1,2-a]pyridine-3-carboxylic acid, ethyl esterMedchemexpress.com
Product Overview: A PI3Kα inhibitor (IC50 = 0.8 nM) that demonstrates antiproliferative activity in T47D, SK-BR-3, and MCF-7 cells with IC50 values of 0.6, 1.5, and 7.8 μM, respectively; induces apoptosis and blocks angiogenesis both in vitro and in vivoHS-173 is
Shipping: wet ice
CAS NO: 192441-08-0 Product: Lomeguatrib
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H18N4O4S
SMILES: O=S(C1=CC=CC=C1)(NC2=CN=CC(C(C=C3)=CN4C3=NC=C4C(OCC)=O)=C2)=OGlucocorticoid Receptor inhibitors
Molecular Weight: 422.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/59/11/7027.abstract
