Product Name: HA-1077 (hydrochloride)
Synonyms: hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine, dihydrochloride FasudilWeb Site：Medchemexpress
Product Overview: A potent inhibitor of ROCK-II, PRK-2, MSK1, and MAPKAP-K1b with IC50 values of 1.9, 4, 5, and 15 µM, respectively; has been shown to reduce blood vessel constriction, decreases pulmonary arterial pressure, inhibit tumor angiogenesis, and improve ins
Shipping: wet ice
CAS NO: 918505-84-7 PLX-4720
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C14H17N3O2S • 2HCl
SMILES: O=S(C1=CC=CC2=CN=CC=C21)(N3CCNCCC3)=OImmunology/Inflammation_Compound_Library inhibitors
Molecular Weight: 364.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/124/21/28
