Product Name: Gliotoxin
Synonyms: 2,3R,5aS,6S-tetrahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-10H-3,10aR-epidithiopyrazino[1,2-a]indole-1,4-dione Aspergillin Medchemexpress.com
Product Overview: An immunosuppressive mycotoxin which inhibits 20S proteasomal chymotrypsin activity (IC50 = 10 μM), preventing activation of NF-κB; induces apoptosis in monocytes and dendritic cells and reduces phagocytosis by neutrophils; inhibits geranylgerany
Shipping: wet ice
CAS NO: 1133432-49-1 GDC-0834
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C13H14N2O4S2
SMILES: O[C@H]1C=CC=C2[C@@H]1N(C([C@]3(CO)N(C)C4=O)=O)[C@@]4(SS3)C2GHSR inhibitors
Molecular Weight: 326.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/54/3/1315.abstract
