Product Name: GSK864
Synonyms: (S)-1-(4-fluorobenzyl)-N3-(4-methoxy-3,5-dimethylphenyl)-7-methyl-5-(1H-pyrrole-2-carbonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3,7-dicarboxamideWeb Site：Medchemexpress
Product Overview: An inhibitor of mutant IDH1 (IC50s = 9, 15, and 17 nM for IDH1 mutants R132C, R132H, and R132G, respectively); causes a dose-dependent reduction in 2-hydroxyglutarate and overcomes the block of differentiation in AML cells expressing mutant IDH1GSK864 is
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CAS NO: 156-54-7 Product: Sodium Butyrate
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C30H31FN6O4
SMILES: O=C(NC1=CC(C)=C(OC)C(C)=C1)C2=NN(CC3=CC=C(F)C=C3)C4=C2CN(C(C5=CC=CN5)=O)C[C@]4(C)C(N)=OMEK inhibitors
Molecular Weight: 558.6
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/47/6/1948.abstract
