Product Name: GSK621
Synonyms: 6-chloro-5-(2-hydroxy-3-methoxy[1,1-biphenyl]-4-yl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dioneMedchemexpress.com
Product Overview: An AMPK activator that reduces the proliferation of AML cell lines (IC50s = 13-30 μM), triggering autophagy via the eIF2α/ATF4 signaling pathwayGSK621 is an activator of AMP-activated protein kinase (AMPK). It has been shown to increase phosphory
Shipping: wet ice
CAS NO: 1206801-37-7 Product: LY2801653 (dihydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C26H20ClN3O5
SMILES: COC1=CC=CC(N2C(C(N(C3=CC=C(C4=CC=CC(OC)=C4O)C=C3)C(Cl)=C5)=C5NC2=O)=O)=C1Mps1 inhibitors
Molecular Weight: 489.9
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/59/11/6975.abstract
