Product Name: GSK503
Synonyms: N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamideMedchemexpress
Product Overview: A selective inhibitor of EZH2 that prevents the methyltransferase activity of wild-type and mutant EZH2 with similar potency (Kiapp = 3-27 nM); effective in vivo in mouse models of cancerThe lysine methyltransferase EZH2 (KMT6), part of the polycomb repre
Shipping: wet ice
CAS NO: 120-97-8 Product: Dichlorphenamide
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C31H38N6O2
SMILES: CN1CCN(C2=NC=C(C3=CC(C(NCC4=C(C)C=C(C)NC4=O)=O)=C(C(C)=CN5C(C)C)C5=C3)C=C2)CC1beta)-catenin inhibitors
Molecular Weight: 526.7
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/58/11/6896.abstract
