Product Name: GSK484 (hydrochloride)
Synonyms: [(3S,4R)-3-amino-4-hydroxy-1-piperidinyl][2-[1-(cyclopropylmethyl)-1H-indol-2-yl]-7-methoxy-1-methyl-1H-benzimidazol-5-yl]-methanoneMedchemexpress.com
Product Overview: A reversible inhibitor of PAD4 (IC50 = 50 nM) that binds to the low-calcium form of the enzyme; blocks the citrullination of PAD4 target proteins in human neutrophils and inhibits the formation of NETs in both mouse and human neutrophilsProtein arginine d
Shipping: wet ice
CAS NO: 224177-60-0 Product: Siramesine (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C27H31N5O3 • HCl
SMILES: O[C@@H]1CCN(C(C2=CC(N=C(C3=CC(C=CC=C4)=C4N3CC5CC5)N6C)=C6C(OC)=C2)=O)C[C@@H]1N.ClCNS-penetrant_Compound_Library inhibitors
Molecular Weight: 510
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/58/11/7003.abstract
