Product Name: GSK481
Synonyms: 5-(phenylmethyl)-N-[(3S)-2,3,4,5-tetrahydro-5-methyl-4-oxo-1,5-benzoxazepin-3-yl]-3-isoxazolecarboxamideMedchemexpress.com
Product Overview: A selective inhibitor of RIP1 that blocks autophosphorylation of Ser166 on wild-type human RIP1 with an IC50 value of 2.8 nM; inhibits RIP1 from human and cynomolgus monkey but is at least 100-fold less potent against non-primate RIP1GSK481 is an inhibito
Shipping: wet ice
CAS NO: 2752-65-0 Product: Gambogic Acid
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H19N3O4
SMILES: O=C(C1=NOC(CC2=CC=CC=C2)=C1)N[C@@H](COC(C=CC=C3)=C3N4C)C4=OO=C(C1=NOC(CC2=CC=CC=C2)=C1)N[C@@H](COC(C=CC=C3)=C3N4C)C4=OCheckpoint Kinase Chk) inhibitors
Molecular Weight: 377.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/59/10/6375.abstract
