Product Name: GSK429286A
Synonyms: N-(6-fluoro-1H-indazol-5-yl)-1,4,5,6-tetrahydro-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-3-pyridinecarboxamideMedchemexpress.com
Product Overview: A cell-permeable inhibitor of ROCK (IC50 = 14 nM); reverses adrenalin-induced contraction of rat aortic rings (IC50 = 190 nM); produces a dose-dependent decrease in mean arterial pressure in spontaneously-hypertensive ratsGSK429286A is a cell-permeable in
Shipping: wet ice
CAS NO: 1017606-66-4 LPA2 antagonist 1
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H16F4N4O2
SMILES: O=C1NC(C)=C(C(NC2=C(F)C=C(NN=C3)C3=C2)=O)C(C4=CC=C(C(F)(F)F)C=C4)C1Phenols inhibitors
Molecular Weight: 432.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/124/21/3423
