Product Name: GSK2193874
Synonyms: 3-([1,4-bipiperidin]-1-ylmethyl)-7-bromo-N-(1-phenylcyclopropyl)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxamideMedchemexpress.com
Product Overview: A potent, selective antagonist of TRPV4 channels, blocking the influx of calcium induced by the TRPV4 agonist GSK634775 with IC50 values of 2, 5, and 40 nM for rat, mouse, and human isoforms, respectively; effective in vivo, as it resolves pulmonary edema
Shipping: wet ice
CAS NO: 304448-55-3 Product: Dynasore
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C37H38BrF3N4O
SMILES: BrC1=CC=C(C(C(NC2(CC2)C3=CC=CC=C3)=O)=C(CN4CCC(N5CCCCC5)CC4)C(C6=CC=CC(C(F)(F)F)=C6)=N7)C7=C1CRM1 inhibitors
Molecular Weight: 691.6
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/59/12/7540.abstract
