Product Name: GSK199 (hydrochloride)
Synonyms: [(3R)-3-amino-1-piperidinyl][2-(1-ethyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-7-methoxy-1-methyl-1H-benzimidazol-5-yl]-methanone, monohydrochlorideWeb Site click
Product Overview: A selective inhibitor of PAD4 (IC50 = 200 nM in the absence of calicum); inhibits the citrullination of PAD4 target proteins and diminishes NET formation in mouse neutrophilsProtein arginine deiminase 4 (PAD4) mediates the transformation of protein argini
Shipping: wet ice
CAS NO: 775351-65-0 Product: Imeglimin
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C24H28N6O2 • HCl
SMILES: N[C@H]1CN(C(C2=CC(N=C(C3=CC(C=CC=N4)=C4N3CC)N5C)=C5C(OC)=C2)=O)CCC1.ClRGS Protein inhibitors
Molecular Weight: 469
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/59/8/4662.abstract
