Product Name: GSK-J4 (hydrochloride)
Synonyms: N-[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine, ethyl ester, monohydrochlorideMedchemexpress
Product Overview: An ethyl ester prodrug of the JMJD3 selective histone demethylase inhibitor GSK-J1; reduces LPS-induced proinflammatory cytokine production, including that of TNFα (IC50 = 9 µM) in human primary macrophagesThe histone H3 lysine 27 (H3K27) deme
Shipping: wet ice
CAS NO: 2016-88-8 Product: Amiloride (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C24H27N5O2 • HCl
SMILES: O=C(OCC)CCNC1=CC(N2CCC(C=CC=C3)=C3CC2)=NC(C4=CC=CC=N4)=N1.ClmGluR inhibitors
Molecular Weight: 454
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/59/1/711.abstract
