Product Name: GSK-J2 (sodium salt)
Synonyms: 3-((6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-3-yl)pyrimidin-4-yl)amino)propanoic acid, monosodium saltWeb Site click
Product Overview: A pyridine regio-isomer of GSK-J1 which poorly inhibits JMJD3 (IC50 > 100 μM), making it an appropriate negative control for in vitro studies involving GSK-J1The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcripti
Shipping: wet ice
CAS NO: 1194044-20-6 LY2811376
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C22H23N5O2 • Na
SMILES: OC(CCNC1=CC(N2CCC(C=CC=C3)=C3CC2)=NC(C4=CC=CN=C4)=N1)=O.[Na]JAK_STAT Signaling inhibitors
Molecular Weight: 412.4
Formulation: A crystalline solid
Purity: ≥90%PubMed ID:http://aac.asm.org/content/54/1/157.abstract
