Product Name: GNF-5837
Synonyms: N-[3-[[2,3-dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N-[2-fluoro-5-(trifluoromethyl)phenyl]-ureaWeb Site click
Product Overview: A potent, bioavailable pan-Trk inhibitor that blocks the proliferation of cells expressing TEL-TrkA, TEL-TrkB, and TEL-TrkC (IC50s = 7, 9, and 11 nM, respectively); inhibits the growth of Ba/F3 and RIE cells expressing both TrkA and NGF with IC50 values o
Shipping: wet ice
CAS NO: 1206524-86-8 Product: MK-5172 (potassium salt)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C28H21F4N5O2
SMILES: FC1=CC=C(C(F)(F)F)C=C1NC(NC2=CC(NC3=CC(NC(/C4=CC5=CC=CN5)=O)=C4C=C3)=C(C)C=C2)=OImidazoline Receptor inhibitors
Molecular Weight: 535.5
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/59/12/7458.abstract
