Product Name: GNE-7915
Synonyms: [4-[[4-(ethylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro-5-methoxyphenyl]-4-morpholinyl-methanoneWeb Site click
Product Overview: A selective, brain-penetrable LRRK2 inhibitor (Kis = 2 and 18.7 nM in biochemical and cell-based assays, respectively); inhibits LRRK2 Ser1292 autophosphorylation in BAC transgenic mice expressing human LRRK2 protein with the G2019S Parkinson’s dise
Shipping: wet ice
CAS NO: 1415925-18-6 GSK2795039
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C19H21F4N5O3
SMILES: CCNC1=C(C(F)(F)F)C=NC(NC2=CC(F)=C(C(N3CCOCC3)=O)C=C2OC)=N1Apoptosis inhibitors
Molecular Weight: 443.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/23/3135
