Product Name: GDC-0623
Synonyms: 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-imidazo[1,5-a]pyridine-6-carboxamideWeb Site：Medchemexpress
Product Overview: A potent, ATP-uncompetitive inhibitor of MEK1 (Ki = 0.13 nM in the presence of ATP); inhibits the proliferation of A375 BRAF(V600E) and HCT116 KRAS(G13D)-mutant cancer cell lines (EC50 = 7 and 42 nM, respectively); upregulates pro-apoptotic BIMGDC-0623 is
Shipping: wet ice
CAS NO: 867331-64-4 Product: TG 100572 (Hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C16H14FIN4O3
SMILES: IC1=CC(F)=C(NC2=C(C(NOCCO)=O)C=CC3=CN=CN23)C=C1Discoidin Domain Receptor inhibitors
Molecular Weight: 456.2
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/60/6/3709.abstract
