Product Name: GDC-0068
Synonyms: (2S)-(4-chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone Medchemexpress
Product Overview: A selective, ATP-competitive, pan-Akt inhibitor that targets Akt1, 2, and 3 (IC50s = 5, 18, and 8 nM, respectivley); blocks Akt signaling both in cultured tumor cell lines and tumor xenograft modelsGDC-0068 is a selective, ATP-competitive, pan-Akt inhibit
Shipping: wet ice
CAS NO: 229005-80-5 Product: TAK-779
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C24H32ClN5O2
SMILES: ClC1=CC=C([C@H](C(N2CCN(C3=NC=NC4=C3[C@H](C)C[C@H]4O)CC2)=O)CNC(C)C)C=C1Bcl-2 Family inhibitors
Molecular Weight: 458
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/59/4/1969.abstract
