Product Name: GDC-0032
Synonyms: 4-[5,6-dihydro-2-[3-methyl-1-(1-methylethyl)-1H-1,2,4-triazol-5-yl]imidazo[1,2-d][1,4]benzoxazepin-9-yl]-α,α-dimethyl-1H-pyrazole-1-acetamide TaselMedchemexpress
Product Overview: A potent inhibitor of PI3K isoforms α, δ, and γ (IC50s = 0.28, 0.12, and 0.97 nM, respectively) that is 31 times less potent at PI3Kβ; has increased potency in cancer cell lines harboring PIK3CA-activating alterations, and is effect
Shipping: wet ice
CAS NO: 457081-03-7 Product: Pyridone 6
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C24H28N8O2
SMILES: CC1=NN(C(C)C)C(C2=CN(CCO3)C(C4=C3C=C(C5=CN(C(C)(C)C(N)=O)N=C5)C=C4)=N2)=N1ATM_ATR inhibitors
Molecular Weight: 460.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/60/3/1546.abstract
