Product Name: Encorafenib
Synonyms: N-[(1S)-2-[[4-[3-[5-chloro-2-fluoro-3-[(methylsulfonyl)amino]phenyl]-1-(1-methylethyl)-1H-pyrazol-4-yl]-2-pyrimidinyl]amino]-1-carbamic acid, methyl ester Medchemexpress
Product Overview: A selective inhibitor of B-RafV600E mutant melanoma cell proliferation (EC50 = 4 nM) with little activity against wild-type B-Raf or a panel of 100 other kinases (IC50s = 900 nM); decreases phosphorylation of the B-Raf substrate MEK at oral doses of 6 mg/
Shipping: wet ice
CAS NO: 898230-59-6 Product: Morinidazole (R enantiomer)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C22H27ClFN7O4S
SMILES: O=C(OC)N[C@@H](C)CNC1=NC(C2=CN(C(C)C)N=C2C3=CC(Cl)=CC(NS(C)(=O)=O)=C3F)=CC=N1G-quadruplex inhibitors
Molecular Weight: 540
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/56/5/2435.abstract
