Product Name: EPZ5676
Synonyms: 9-[5-deoxy-5-[[cis-3-[2-[6-(1,1-dimethylethyl)-1H-benzimidazol-2-yl]ethyl]cyclobutyl](1-methylethyl)amino]-β-D-ribofuranosyl]-9H-purin-6-amineWeb Site：Medchemexpress
Product Overview: A highly potent and selective inhibitor of DOT1L histone methyltransferase activity (Ki = 80 pM); inhibits the H3K79 methylation in various human leukemia cell lines (IC50s = 3-5 nM), decreasing MLL-fusion target gene expression and inhibiting proliferati
Shipping: wet ice
CAS NO: 1092578-46-5 (3R,4S)-Tofacitinib
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C30H42N8O3
SMILES: CC(C)N(C[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O1)[C@@H]4C[C@H](CCC5=NC(C=CC(C(C)(C)C)=C6)=C6N5)C4Protease_Inhibitor_Cocktail inhibitors
Molecular Weight: 562.7
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/124/21/43
