Product Name: EPZ004777 (formic acid salt)
Synonyms: 7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, monoformic acid saltMedchemexpress.com
Product Overview: A potent DOT1L inhibitor (IC50 = 400 pM) that selectively kills (MLL) cells in vitro and prolongs survival in an MLL xenograft mouse model; accelerates the reprogramming of somatic cells into induced pluripotent stem cellsDOT1L is a protein methyltransfer
Shipping: wet ice
CAS NO: 211555-08-7 Product: WHI-P180
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C28H41N7O4 • CH2O2
SMILES: CC(C)(C)C1=CC=C(NC(NCCCN(C(C)C)C[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C=CC4=C3N=CN=C4N)O2)=O)C=C1.[H]C(O)=OMonoamine Transporter inhibitors
Molecular Weight: 585.7
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/59/8/4870.abstract
