Product Name: Deltarasin (hydrochloride)
Synonyms: 2-[4-[(2S)-2-(2-phenyl-1H-benzimidazol-1-yl)-2-(4-piperidinyl)ethoxy]phenyl]-1-(phenylmethyl)-1H-benzimidazole, hydrochlorideWeb Site click
Product Overview: A small molecule that binds to the farnesyl-binding pocket of PDEδ (Kd = 41 nM) in cells thus inhibiting its interaction with KRAS and disrupting RAS signaling; reduces proliferation and increases cell death of Panc-Tu-I tumor cells at 5 μM in a
Shipping: wet ice
CAS NO: 847591-62-2 ICG-001
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C40H37N5O • 2.4HCl
SMILES: C12=CC=CC=C1N=C(C3=CC=CC=C3)N2[C@@H](C4CCNCC4)COC5=CC=C(C6=NC(C=CC=C7)=C7N6CC8=CC=CC=C8)C=C5.Cl.ClEGFR inhibitors
Molecular Weight: 691.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/116/21/258
