Product Name: Danusertib
Synonyms: 4-(4-methyl-1-piperazinyl)-N-[1,4,5,6-tetrahydro-5-[(2R)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3-yl]-benzamide PHA-739358Web Site click
Product Overview: A pan-Aurora kinase inhibitor (IC50s = 13, 79, and 61 nM for Aurora A, B, and C, respectively) that also targets Abl, Ret, Trka and FGFR1 (IC50s = 25, 31, 31, and 47 nM, respectively); exhibits anti-proliferative and pro-apoptotic activity against a panel
Shipping: wet ice
CAS NO: 1283000-43-0 Product: MK-8033 (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C26H30N6O3
SMILES: CN1CCN(C2=CC=C(C(NC3=NNC4=C3CN(C([C@H](OC)C5=CC=CC=C5)=O)C4)=O)C=C2)CC1Autophagy inhibitors
Molecular Weight: 474.6
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/59/6/3240.abstract
