Product Name: Dabrafenib
Synonyms: N-[3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-benzenesulfonamide GSK2118436Web Site click
Product Overview: A selective inhibitor of mutant B-RafV600E (IC50 = 0.8 nM), with 4- and 6-fold reduced potency against wild type B-Raf and c-Raf (IC50s = 3.2 and 5 nM, respectively); studied in clinical trials in patients with B-RafV600E metastatic melanoma and other sol
Shipping: wet ice
CAS NO: 441045-17-6 Eribulin (mesylate)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C23H20F3N5O2S2
SMILES: FC1=C(C2=C(C3=CC=NC(N)=N3)SC(C(C)(C)C)=N2)C=CC=C1NS(C4=C(F)C=CC=C4F)(=O)=OCCR inhibitors
Molecular Weight: 519.6
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/18/2479
