Product Name: Compound E
Synonyms: N-[(1S)-2-[[(3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-benzeneacetamide γ-SecretaseWeb Site：Medchemexpress
Product Overview: A potent, cell-permeable, and selective inhibitor of γ-secretase, blocking the cleavage of both APP and Notch CTFs with IC50 values of ~0.3 nM; induces neuronal differentiation, impairs ovarian folliculogenesis, and suppresses thymocyte development
Shipping: wet ice
CAS NO: 153437-55-9 Product: WHI-P180 (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C27H24F2N4O3
SMILES: O=C1[C@@H](NC([C@H](C)NC(CC2=CC(F)=CC(F)=C2)=O)=O)N=C(C3=CC=CC=C3)C4=C(C=CC=C4)N1CiGluR inhibitors
Molecular Weight: 490.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/59/8/4695.abstract
