Product Name: Cobimetinib
Synonyms: [3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl][3-hydroxy-3-(2S)-2-piperidinyl-1-azetidinyl]-methanone GDC-0973 Web Site click
Product Overview: A selective, orally available inhibitor of MEK1 (IC50 = 4.2 nM); induces differentiation and apoptosis in cancer cells linesCobimetinib is a potent, orally available inhibitor of MEK1 (IC50 = 4.2 nM). It shows more than 100-fold selectivity for MEK when
Shipping: wet ice
CAS NO: 1415800-43-9 Product: UNC1215
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H21F3IN3O2
SMILES: FC1=C(NC2=CC=C(I)C=C2F)C(C(N3CC([C@@H]4CCCCN4)(O)C3)=O)=CC=C1FMAGL inhibitors
Molecular Weight: 531.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/59/9/5159.abstract
