Product Name: Ceritinib
Synonyms: 5-chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine LDK 378Medchemexpress
Product Overview: An inhibitor of ALK with an IC50 value of 200 pM in enzymatic assays; inhibits ALK in cells (IC50 = 25 nM) and in vivo, producing tumor regression in a rat xenograft modelCeritinib is an inhibitor of anaplastic lymphoma kinase (ALK) with an IC50 value of
Shipping: wet ice
CAS NO: 179324-69-7 Product: Bortezomib
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C28H36ClN5O3S
SMILES: CC(C=C(NC1=NC=C(Cl)C(NC2=CC=CC=C2S(C(C)C)(=O)=O)=N1)C(OC(C)C)=C3)=C3C4CCNCC4CDK inhibitors
Molecular Weight: 558.1
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/60/3/1608.abstract
