Product Name: CYT387
Synonyms: N-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]-benzamide MomelotinibMedchemexpress.com
Product Overview: An ATP-competitive inhibitor of JAK1 and JAK2 (IC50s = 11 and 18 nM, respectively); causes growth suppression and apoptosis in JAK2-dependent hematopoietic cell lines; is efficacious in a mouse model of JAK2V617F-dependent myeloproliferative neoplasmsCYT3
Shipping: wet ice
CAS NO: 0 WEHI-539 (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C23H22N6O2
SMILES: O=C(NCC#N)C(C=C1)=CC=C1C2=NC(NC(C=C3)=CC=C3N4CCOCC4)=NC=C2MNK inhibitors
Molecular Weight: 414.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/54/4/1639.abstract
