Product Name: CGK733
Synonyms: α-phenyl-N-[2,2,2-trichloro-1-[[[(4-fluoro-3-nitrophenyl)amino]thioxomethyl]amino]ethyl]-benzeneacetamide ATM/ATR Kinase InhibitorWeb Site click
Product Overview: An inhibitor of ATR and ATM kinases (IC50 = ~ 200 nM) that induces cell death in prematurely senescent breast, lung, and colon cancer cellsAtaxia-telangiectasia mutated (ATM) and ATM- and Rad3-related (ATR) kinases mediate the DNA damage response pathway
Shipping: wet ice
CAS NO: 1303607-07-9 MI-773
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C23H18Cl3FN4O3S
SMILES: FC1=C([N+]([O-])=O)C=C(NC(NC(C(Cl)(Cl)Cl)NC(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)=S)C=C1Aldehyde Dehydrogenase ALDH) inhibitors
Molecular Weight: 555.8
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/14/2021
