Product Name: CB-5083
Synonyms: 1-[7,8-dihydro-4-[(phenylmethyl)amino]-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamideMedchemexpress
Product Overview: An orally bioavailable inhibitor of p97 (IC50 = 11 nM); causes accumulation of poly-ubiquitinated proteins, retention of ERAD substrates, and activation of the apoptotic arm of the unfolded protein responseCB-5083 is an orally bioavailable inhibitor of p9
Shipping: wet ice
CAS NO: 1184940-47-3 Product: EMD638683 (R-Form)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C24H23N5O2
SMILES: CC1=CC2=C(C=CC=C2C(N)=O)N1C3=NC(CCOC4)=C4C(NCC5=CC=CC=C5)=N3Antifolate inhibitors
Molecular Weight: 413.5
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/60/8/4482.abstract
