Product Name: Bisindolylmaleimide X (hydrochloride)
Synonyms: 3-[8-(aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione, monohydrochloride BIM X Web Site click
Product Overview: A cell-permeable, reversible, ATP-competitive PKC inhibitor (IC50 = 15 nM, rat brain PKC); inhibits PKCα, βI, βII, γ, and ε with IC50 values of 8, 8, 14, 13, and 39 nM, respectively; also inhibits Cdk2 (IC50 = 200 nM) and GSK
Shipping: wet ice
CAS NO: 1616632-77-9 TIC10
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C26H24N4O2 • HCl
SMILES: O=C(N1)C(C2=CN(C)C3=C2C=CC=C3)=C(C4=C5N(CCC(CN)C5)C6=C4C=CC=C6)C1=O.ClAMPK inhibitors
Molecular Weight: 461
Formulation: A red solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/2/136
