Product Name: BMS-265246
Synonyms: (4-butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(2,6-difluoro-4-methylphenyl)-methanoneMedchemexpress.com
Product Overview: A cell-permeable inhibitor of Cdk1/cyclin B and Cdk2/cyclin E (IC50s = 6 and 9 nM, respectively); blocks the cycling of HCT116 cells (EC50 = 0.29-0.49 µM)Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore
Shipping: wet ice
CAS NO: 1033769-28-6 Product: GNF-5837
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C18H17F2N3O2
SMILES: CC1=CC(F)=C(C(C2=C(OCCCC)C(C=NN3)=C3N=C2)=O)C(F)=C1EGFR inhibitors
Molecular Weight: 345.3
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/59/8/5003.abstract
