Product Name: BAY 598
Synonyms: (S,Z)-N-(1-(N-cyano-N-(3-(difluoromethoxy)phenyl)carbamimidoyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl)-N-ethyl-2-hydroxyacetamideWeb Site click
Product Overview: A selective inhibitor of SMYD2 with IC50 values of 27 nM and in vitro and in whole cells, respectively; exhibits 100-fold selectivity for SMYD2 over other enzymes testedBAY 598 is a selective inhibitor of SMYD2. It inhibits the methylation of p53 at lysin
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CAS NO: 1429881-91-3 Product: UNC2025
Stability: Store at 2-8 degrees; shelf life 730 days maximum after production
Molecular Formula: C22H20Cl2F2N6O3
SMILES: ClC1=C(Cl)C=CC(C2=NN(/C(NC3=CC=CC(OC(F)F)=C3)=NC#N)C[C@@H]2N(C(CO)=O)CC)=C1TGF-beta_Smad inhibitors
Molecular Weight: 525.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/48/3/753.abstract
