Product Name: Axitinib
Synonyms: N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide AG-013736Web Site click
Product Overview: A tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively); causes regression of fenestrated, VEGFR-rich capillaries in tumors and normal tissue of miceA
Shipping: wet ice
CAS NO: 1135237-88-5 Exherin (trifluoroacetate)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C22H18N4OS
SMILES: O=C(NC)C1=C(SC2=CC3=C(C(/C=C/C4=NC=CC=C4)=NN3)C=C2)C=CC=C1Adrenergic Receptor inhibitors
Molecular Weight: 386.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/18/2459
