Product Name: Avagacestat
Synonyms: (2R)-2-[[(4-chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoro-pentanamide BMS 708163Medchemexpress
Product Overview: A potent, orally bioavailable inhibitor of γ-secretase that more potently inhibits the cleavage of APP to Aβ40 than signaling through Notch (IC50s = 0.30 and 58 nM, respectively); shows good pharmacokinetics in rats, dogs, and humans and passes
Shipping: wet ice
CAS NO: 161715-21-5 Tebipenem
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C20H17ClF4N4O4S
SMILES: O=S(N([C@@H](C(N)=O)CCC(F)(F)F)CC1=CC=C(C2=NOC=N2)C=C1F)(C3=CC=C(Cl)C=C3)=OImidazoline Receptor inhibitors
Molecular Weight: 520.9
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/54/3/1369.abstract
