Product Name: Almorexant (hydrochloride)
Synonyms: (αR,1S)-3,4-dihydro-6,7-dimethoxy-N-methyl-α-phenyl-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-2(1H)-isoquinolineacetamide, monohydrochloride ACT 078573Medchemexpress
Product Overview: A dual orexin 1 and 2 receptor antagonist (Kds = 1.3 and 0.17 nM, respectively); 100 mg/kg promotes nonrapid eye movement sleep and exacerbates cataplexy in a mouse model of narcolepsyAlmorexant is a dual antagonist of the orexin 1 and 2 receptors (Kds =
Shipping: wet ice
CAS NO: 182431-12-5 Lomitapide
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C29H31F3N2O3 • HCl
SMILES: O=C(NC)[C@@H](C1=CC=CC=C1)N2CCC3=C(C=C(OC)C(OC)=C3)[C@@H]2CCC4=CC=C(C(F)(F)F)C=C4Apoptosis inhibitors
Molecular Weight: 549.02
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/22/2951
