Product Name: Akt Inhibitor VIII
Synonyms: 1,3-dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-oneWeb Site click
Product Overview: A potent, allosteric inhibitor of Akt1 and Akt2 (IC50 = 58 and 210 nM, respectively) that less effectively blocks Akt3 activity (IC50 = 2.2 µM); cell permeable, blocking insulin regulation of FOXO1 activity at 1 µM in rat hepatoma cellsThree r
Shipping: wet ice
CAS NO: 1373422-53-7 Product: GSK-J1
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C34H29N7O
SMILES: O=C1NC2=C(C=CC=C2)N1C(CC3)CCN3CC4=CC=C(C5=NC(C=C(NC=N6)C6=C7)=C7N=C5C8=CC=CC=C8)C=C4Porcupine inhibitors
Molecular Weight: 551.7
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/58/1/503.abstract
