Product Name: Afatinib (BIBW2992) Dimaleate
Synonyms: Medchemexpress.com
Product Overview: Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant.
Shipping: wet ice
CAS NO: 1256580-46-7 Product: CH5424802
Stability: Store at +4 degrees; shelf life 730 days maximum after production
Molecular Formula: C32H33ClFN5O11
SMILES: P-glycoprotein inhibitors
Molecular Weight: 718.08
Formulation: solution 10mM in DMSO
Purity: 0.98PubMed ID:http://aac.asm.org/content/61/3/e02296-16.abstract
