Product Name: AZD 6244
Synonyms: 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide ARRY-142886 Medchemexpress
Product Overview: A potent, highly selective inhibitor of MEK1 and MEK2 (IC50 = 14-99 and 530 nM, respectively); weakly inhibits EGFR (IC50 = 7.0 µM) and has no effect on a large panel of other kinases; suppresses growth and induces apoptosis and differentiation with
Shipping: wet ice
CAS NO: 912545-86-9 Product: SAG
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C17H15BrClFN4O3
SMILES: CN(C=N1)C2=C1C(F)=C(NC3=CC=C(Br)C=C3Cl)C(C(NOCCO)=O)=C2MAPK_Compound_Library inhibitors
Molecular Weight: 457.7
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/57/4/1823.abstract
